Single Particle CryoEM: Potential for Further Improvement

Fabs enable single particle cryoEM studies of small proteins.

In spite of its recent achievements, the technique of single particle electron cryomicroscopy (cryoEM) has not been widely used to study proteins smaller than 100 kDa, although it is a highly desirable application of this technique. One fundamental limitation is that images of small proteins embedded in vitreous ice do not contain adequate features for accurate image alignment. We describe a ge...

Single Particle CryoEM of the Anthrax Toxin Initial Engagement Complex

The lethality of anthrax, a zoonotic disease and bioterrorism agent, is due to the anthrax toxin. This tripartitate toxin consists of protective antigen (PA), lethal factor (LF), and edema factor (EF). The 440 kDa heptameric PA prepore binds up to three molecules of LF, a mitogen-activated protein kinase kinase protease, and/or EF, an adenylate cyclase. This entire complex, bound to receptor pr...

application of upfc based on svpwm for power quality improvement

در سالهای اخیر،اختلالات کیفیت توان مهمترین موضوع می باشد که محققان زیادی را برای پیدا کردن راه حلی برای حل آن علاقه مند ساخته است.امروزه کیفیت توان در سیستم قدرت برای مراکز صنعتی،تجاری وکاربردهای بیمارستانی مسئله مهمی می باشد.مشکل ولتاژمثل شرایط افت ولتاژواضافه جریان ناشی از اتصال کوتاه مدار یا وقوع خطا در سیستم بیشتر مورد توجه می باشد. برای مطالعه افت ولتاژ واضافه جریان،محققان زیادی کار کرده ...

The Single Particle Potential in Mean-Field Theory

Improvement Strategies for Monte Carlo Particle Filters

The particle filtering field has seen an upsurge in interest over recent years and accompanying this a number of enhancements to the basic techniques have been suggested in the literature. In this paper we collect together a group of these developments which seem to be particularly important for time series applications and give a broad discussion of the methods, showing the interrelationships ...